■<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN"> <html> <head> <title>Cinnamon Extract</title> <META NAME="description" CONTENT="Cinnamon Extract is derived from cinnamon spice which comes from the bark of the Cinnamon plant (Cinnamomum). Cinnamon Extract is being studied for the treatment of Diabetes, Cancer, viruses, Alzheimer's Disease and Arthritis. Cinnamon Extract and Honey is a new twist to a popular treatment for Diabetes."> <META NAME="keywords" CONTENT="cinnamon extract, Cinnamon Extract"> <META NAME="google-site-verification" content="1TQ0S-4QLfgpYL_iqOHXBLJLJIjFLcNEaNMBJaGUC88" /> <META NAME="viewport" CONTENT="width=device-width, initial-scale=1"> <script type="text/javascript"> var _gaq = _gaq || []; _gaq.push(['_setAccount', 'UA-10967855-15']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); </script> </head> <body bgcolor="#FFFAEF"> <table bgcolor="#FFA500" width=865 align=center border=0 cellpadding=5> <tr><td colspan="1" bgcolor="#FFA500" border=0> <h1>Cinnamon Extract</h1></td> <td align="right" bgcolor="#FFA500" border=0> <form action="http://www.google.com/cse" id="cse-search-box"> <div> <input type="hidden" name="cx" value="partner-pub-3161100571814651:2816207497" /> <input type="hidden" name="ie" value="UTF-8" /> <input type="text" name="q" size="35" /> <input type="submit" name="sa" value="Search" /> </div> </form> <script type="text/javascript" src="http://www.google.com/coop/cse/brand?form=cse-search-box&amp;lang=en"></script> <script type="text/javascript" src="http://www.google.com/cse/query_renderer.js"></script> <div id="queries"></div> <script src="http://www.google.com/cse/api/partner-pub-3161100571814651/cse/2816207497/queries/js?oe=UTF-8&amp;callback=(new+PopularQueryRenderer(document.getElementById(%22queries%22))).render"></script> </td></tr> </table> <table bgcolor="#FFE4B3" width=865 align=center border=0 cellpadding=5> <tr><td colspan=1> <script type="text/javascript"><!-- google_ad_client = "ca-pub-3161100571814651"; /* 336x280, created 6/30/10 */ google_ad_slot = "8849792571"; google_ad_width = 336; google_ad_height = 280; //--> </script> <script type="text/javascript" src="http://pagead2.googlesyndication.com/pagead/show_ads.js"> </script> </td> <td colspan=1> <B>Cinnamon Extract</B> is an extract from cinnamon spice which itself is obtained from the inner bark of the cinnamon plant. It is currently being studied for its effects on Diabetes, Cancer, viruses, Alzheimer's Disease and Arthritis. <p><b>Botanical Classification of the Plant Sources:</b> <UL> <LI>Family: Lauraceae <LI>Genus: Cinnamomum <LI>Species: Verum, Cassia <LI> Full Names: Cinnamomum Verum and Cinnamomum Cassia </UL> <P> <b>Distribution:</b><br> <UL> <LI>Cinnamomum Verum: Sri Lanka <LI>Cinnamomum Cassia: Southeast Asia and China. </UL> </td></tr> <tr><td colspan="2"> <h3>Properties of Cinnamon Extract:</h3> <UL> <LI>antiviral; <LI>antioxidant; <LI>anti-bacterial and anti-fungal; <LI>anti-inflamatory; <LI>insulin mimetic (imitates insulin); lowers blood glucose levels in humans; <LI>anti-amyloid; inhibits Alzheimer's disease in mice. </UL> </td></tr> </table> <table bgcolor="#FFE4B3" width=865 align=center border=0 cellpadding=5> <tr colspan="2"><td colspan="1"> <h3>Scientific Data on Cinnamon:</h3> <UL> <LI>Synonyms for Cinnamon Verum: "Ceylon Cinnamon" (Cinnamomum Zeylanicum) and "True Cinnamon". <LI>Synonyms for Cinnamon Cassia: "Cassia". <LI>Select Chemical Ingredients: <UL><LI> Methylhydroxy Chalcone Polymer (MHCP). <LI> Procyanidin-B2 (also found in chinchona bark [quinine], vine leaves, apples, dark chocolate, green tea). <LI> Cinnamaldehyde (contained in the natural oil of the bark). <LI> Coumarin, which is high in the Cassia form and low in the Ceylon form. </UL> <LI>To obtain Cinnamon Extract: a simple warm water extraction from the spice or bark is all that is required. </UL> </td> <td bgcolor="#FFA500" colspan="1" width="300"><IMG SRC="cinnamonextract.jpg" ALT="cinnamon extract" width="300" height="180" align=left><BR CLEAR="all"><font size="2">Cinnamon Extract</font> </td></tr> <tr colspan="2"><td colspan="1"> <h3>The Plant: Cinnamomum</h3> <UL> <LI>height: an evergreen plant that grows to 10-15m tall; <LI>leaves: ovate-oblong in shape, 7 18 cm; <LI>flowers: loosely-branched flower-cluster with greenish color; <LI>fruit: a 1cm berry of purple color; <LI>bark: the inner bark is the source of cinnamon spice. </UL> </td> <td bgcolor="#FFA500" colspan="1" width="300"><IMG SRC="cinnamonspice.jpg" ALT="cinnamon spice" width="300" height="180" align="left"><BR CLEAR="all"><font size="2">Cinnamon Spice</font> </td></tr> </table> <table bgcolor="#FFE4B3" width=865 align=center border=0 cellpadding=5> <tr colspan="2"><td colspan="1"> <h3>Historical Uses of Cinnamon:</h3> <UL> <LI>In English speaking countries: <UL><LI>a mixture of Cinnamon and Honey has been used for a variety of illnesses: heart ailments, indigestion, bladder infection, toothache, arthritis and colds. Cinnamon and Honey was also seen as promoting longevity. More recently it is seen as lowering cholesterol, lowering weight and treating diabetes type II. <LI>some recent scientific research has recommended the use of cinnamon extract. However, a 2012 review of this research has criticised the scope of the previous review and the quality of the earlier studies. A debate has begun over the use of cinnamon extract for the treatment of Diabetes Type 2 and we shall have to wait for further clarifications before recommending it. <LI><B>Recipe for Cinnamon Extract and Honey</B>: the extract can be made by making a tea of the cinnamon spice or quills using warm rather than hot water as this will dissolve only the required parts; the residue can then be strained and filtered. Allow the honey to dissolve properly into the strained cinnamon water. By extracting MHCP from the natural cinnamon spice, the remaining unwanted parts of the cinnamon can be removed, thus lowering the burden on the liver and kidneys. </UL> <LI>In Japan: the traditional medicine "Maoto" (╗×─×dl) has been in customary use to treat influenza. Maoto granules include cinnamon extract. </UL> </td> <td colpsan="1"><td bgcolor="#FFA500" colspan="1" width="300"><IMG SRC="cinnamonbark.jpg" ALT="Cinnamon Bark" width="300" height="280" align=left><BR CLEAR="all"><font size="2">Cinnamon Bark</font><BR><BR> <script type="text/javascript"><!-- google_ad_client = "ca-pub-3161100571814651"; /* MedRect-20Jun13 */ google_ad_slot = "4232872692"; google_ad_width = 300; google_ad_height = 250; //--> </script> <script type="text/javascript" src="http://pagead2.googlesyndication.com/pagead/show_ads.js"> </script> </td></tr> </table> <table bgcolor="#FFE4B3" width=865 align=center border=0 cellpadding=5> <tr><td colspan=1 bgcolor=#FFA500> <H2>From Research Articles on Cinnamon Extract</H2></td></tr> <tr><td colspan=1> <UL> <LI>Diabetes <UL><LI>Article 1: In this study, the authors showed that procyanidin-B2 is the active component of cinnamon involved in AGE (Advanced Glycation End-products) inhibition using eye lens proteins under in vitro conditions. The data indicate that procyanidin-B2 enriched fraction scavenges dicarbonyls. Also procyanidin-B2 fraction of cinnamon inhibited the formation of glycosylated hemoglobin in human blood under ex vivo conditions. The authors also demonstrated the physiological significance of procyanidin-B2 fraction in terms of delay of diabetic cataract through inhibition of AGE in diabetic rats. <B>These findings establish the antiglycating potential of procyanidin-B2 fraction of cinnamon which suggests a scope for controlling AGE-mediated diabetic complications by food sources that are rich in proanthocyanidins like procyanidin-B2.</B><br> <font size="1"> Source: PMID: 24136906 (Hyderabad, India, 2013) </font> <LI>Article 2: In a study of the effect of a water extract of cinnamon on toxic aggregation of human islet amyloid polypeptide (hIAPP). The misfolding of hIAPP was considered a causative factor of type 2 diabetes mellitus. They investigated whether cinnamon had any beneficial effect on the toxic aggregation of hIAPP. They found that cinnamon water extract inhibited the amyloid formation of hIAPP in a dose-dependent manner, and identified proanthocyanidins as the major anti-amyloidogenic compounds of the cinnamon extract. Proanthocyanidins inhibited the development of the toxic amyoid aggregates and attenuated their membrane damaging and cytotoxic effects.<BR> <font size="1"> Source: PMID: 23499750 (Wuhan, China, 2013) </font> <LI>Article 3: In a study of 66 people with type 2 diabetes, the conclusion drawn was that both hemoglobin A(1c) and fasting blood glucose levels were significantly reduced in patients who took low-dose and high-dose cinnamon extract.<br> <font size="1"> Source: PMID: 22749176 (Shanghai, China, 2012) </font> <LI>Article 4 (Review): In a review of 6 clinical trials (up to Jan 2011) that included a total of 435 patients with type 2 diabetes, the conclusion drawn was that the use of cinnamon showed a beneficial effect on glycaemic control (both HbA1c and FPG).<br> <font size="1"> Source: PMID: 22579946 (Brentford, UK, 2012) </font> <LI>Article 5 (Review): The authors of a 2012 Review concluded that cinnamon was no more effective than placebo, another active medication or no treatment in reducing glucose levels and glycosylated haemoglobin A1c (HbA1c), a long-term measurement of glucose control. The authors called for further studies of a more rigorous kind to examine the effects of cinnamon on diabetes type I and type II.<br> <font size="1"> Source: DOI: 10.1002/14651858.CD007170.pub2 (Cochrane, 2012) </font> <LI>Article 6: In a study of 60 people with type 2 diabetes, the researchers concluded that the intake of 1, 3, or 6 g of cinnamon per day reduced serum glucose, triglyceride, LDL cholesterol, and total cholesterol in people with type 2 diabetes. In 40 days, all three levels of cinnamon reduced the mean fasting serum glucose by 18-29%, triglyceride by 23-30%, LDL cholesterol by 7-27%, and total cholesterol by 12-26%.<br> <font size="1"> Source: PMID: 14633804 (Peshawar, Pakistan, 2003) </font> </UL> <LI>Alzheimer's Disease <UL><LI>Article 1: In a study of flies and mice which had a been bred for Alzheimer's disease an extract of cinnamon was administered and the results showed that the extract restored their natural longevity and locomotion and totally abolished larger species of Amyloid-beta (A▓) in their brain accompanied by improvement in cognitive behavior.<br> <font size="1"> Source: PMID: 21305046 (Tel Aviv, Israel, 2011) </font></UL> <LI>Cancer <UL><LI>Article 1: In experiments with mice that had human melanoma, it was found that the cinnamon-derived dietary Michael acceptor trans-cinnamic aldehyde (CA) impairs melanoma cell proliferation and tumor growth. However, large doses were required.<br> <font size="1"> Source: PMID: 19000754 (Tucson, USA, 2009) </font> <LI>Article 2: In experiments with mice that had been given tumor necrosis factor alpha (TNF-alpha), it was found that a water extraction of cinnamon decreased the TNF-alpha in the serum of the mice. Its effects were stronger in those fractions of the cinnamon extract which contained the higher doses of the natural polyphenol.<br> <font size="1"> Source: PMID: 23190501 (Yongin, South Korea, 2012) </font></UL> <LI>Arthritis <UL><LI>Article 1: In an experiment with rats, a polyphenol fraction of Cinnamomum Zeylanicum bark demonstrated a strong and dose-dependent reduction of inflamation and arthritis. It also reduced writhing (a symptom of pain), swelling and granules in the paws of the rodents, without causing ulcers.<BR> <font size="1"> Source: PMID: 23833722 (Pune, India, 2013) </font></UL> </UL> </td></tr> <tr><td colspan="1" align="center"> <script type="text/javascript"><!-- google_ad_client = "ca-pub-3161100571814651"; /* Leaderboard728x90Image */ google_ad_slot = "6148683044"; google_ad_width = 728; google_ad_height = 90; //--> </script> <script type="text/javascript" src="http://pagead2.googlesyndication.com/pagead/show_ads.js"> </script> <script type="text/javascript"><!-- google_ad_client = "ca-pub-3161100571814651"; /* Wide link */ google_ad_slot = "3290598114"; google_ad_width = 728; google_ad_height = 15; //--> </script> <script type="text/javascript" src="http://pagead2.googlesyndication.com/pagead/show_ads.js"> </script> </td></tr> </table> <table bgcolor="#FFE4B3" align="center" width="65%" border="0" cellpadding="14"> <tr><td colspan="3"><HR size="20" width="100%" color="#FFFA500"></td></tr> <tr><td colspan="2"> <h3 align="center"><a href="http://www.oldherbs-newscience.com">Old Herbs - New Science</a></h3> </td></tr> <tr><td colspan-"1"> <a href="http://www.ananain.com">Ananain and Comosain</a> (from Pineapple stem)<BR><BR> <a href="http://www.cinnamonextract.net">Cinnamon Extract</a><BR><BR> <a href="http://www.curcumalonga.com">Curcuma Longa</a><BR><BR> <a href="http://www.curcumenol.com">Curcumenol</a><BR><BR> <a href="http://www.ficain.com">Ficain</a> (from Fig Trees)<BR><BR> <a href="http://www.licoricerootextract.com">Licorice Root Extract</a><BR><BR> <a href="http://www.pettyspurge.com">Petty Spurge</a> and <a href="http://www.euphorbiapeplus.com">Euphorbia Peplus</a><BR><BR> </td> <td colspan=1> <a href="http://www.rosmarinicacid.com">Rosmarinic Acid</a> (from Rosemary, Sage)<BR><BR> <a href="http://www.spanishsage.com">Spanish Sage</a><BR><BR> <a href="http://www.turmericextract.com">Turmeric Extract</a><BR><BR> <a href="http://www.vineatrol.com">Vineatrol</a> (from Grapevine shoots)<BR><BR> <a href="http://www.withaniasomnifera.com">Withania Somnifera</a> (Ashwagandha)<BR><BR> <a href="http://www.withanolide.com">Withanolide</a> (from Ashwagandha)<BR><BR> <a href="http://www.zerumbone.com">Zerumbone</a> (from Ginger) </td></tr> </table> <table bgcolor="#FFA500" width=865 align=center border=0 cellpadding=5> <tr><td colspan="2"><font size="2">This website acknowledges Pubmed (www.ncbi.nlm.nih.gov) as source for medical research abstracts.<BR><BR>These statements have not been evaluated by the FDA. 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